S outcomes on unmeasured anions.P284 Hybrid renal alternative procedures vs ongoing haemodiafiltration in haemodynamically unstable patientsP Marcelino, D Sargento, A Fernandes, S Marum Healthcare facility Curry Cabral, Lisbon, Portugal Crucial Treatment 2006, 10(Suppl one):P284 (doi: ten.1186/cc4631) Introduction Acute renal failure while in the significant care location is a frequent and troublesome issue which will result in sizeable morbidity and mortality. It can be generally component of multiorgan failure having an expressive burden from the ICU. Aims The authors present a retrospective review evaluating a hybrid renal replacement procedure (HRRT) vs a ongoing renal substitution technique (CRRT) in two teams of haemodynamically unstable individuals admitted on the medical/surgical ICU. Products and approaches One group (n = 26) been given HRRT all through 2003 plus the other (n = 27) gained CRRT for the duration of 2004, the 12 months of implementation of HRRT inside our ICU. Severity scores (SAPS II, APACHE II, Sofa and MODS), fundamental condition and haemodynamic parameters ended up thought of. Descriptive statistical evaluation was done because of the suggest and conventional deviation for every parameter. Distinctions amongst numerical variables have been analysed by Student's t take a look at or making use of the Mann hitney check. Multiple regression examination was performed to evaluated distinctions in mortality. Effects Both equally teams of patients experienced equivalent severity scores, DOTATATE fundamental disorders and haemodynamic profile (Table one). The urea and creatinine reduction rates (UUR and CRR) had been also evaluated. Individuals handled with HRRT confirmed a lessen mortality (sixty two vs eighty four ), a lot less heparin need to have, along with a increased URR and CRR. Odds for mortality during the CRRT group have been about thrice higher (95 CI, 0.86?two.11), but not statistically sizeable (P = 0.074) (Desk 2). Summary HRRT is usually a legitimate alternative to CRRT in haemodynamically unstable critically sick clients. Even further studies areTable one (abstract P284) Parameter CRRT (team 1) HRRT (group 2) 27 61.seven ?16.five 19.three ?18.6 13.1 ?six.six seventeen (62 ) 30.ePubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/2878751PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/2878751 ID:https://www.ncbi.nlm.nih.gov/pubmed/21804710 0.six 0.P283 Metabolic disturbances encountered all through pediatric steady renal alternative therapyD Soysal, A Nayir, M Karabocuoglu, A Citak, R Ucsel, N Uzel Istanbul Clinical Faculty, Istanbul, Turkey Critical Care 2006, 10(Suppl one):P283 (doi: ten.1186/cc4630) Objective Continual renal substitute therapy (CRRT) has become a significant supportive treatment for critically unwell young children with acute renal failure. In Turkey commercially available diafiltration and alternative fluids are not able to be observed available on the market. Instead, peritoneal dialysis fluids for dialysis and usual saline as substitute fluid are used. The first objective of the analyze would be to study the metabolic troubles thanks to CRRT solutions. The second goal should be to establish demographic traits and results with the patients that receive CRRT. Procedures A retrospective chart critique inside a college clinic. People All pediatric sufferers dealt with with CRRT in between February 2004 and December 2004. Measurements and benefits Thirteen clients gained CRRT; 7 survived (53.eight ). All people were being treated with steady veno-venous hemodiafiltration. The median patient age was 71.8 ?seventy eight.8 (one.5?80) months. Blood flow premiums varied from twenty to one hundred fifty ml/min. Ultrafiltration and dialysis level ranges have been ninety?thirty ml/1.seventy three m2/hour and two hundred?085 ml/1.seventy three m2/hour, respectively. The alternative fluid dose was 17.one ?13.5 ml/kg/hour.